Indigenous peoples globally are seeking new ways in which to communicate and share our worldviews.Sometimes defined as resistance research, emancipatory research, decolonising research - our research (re)presents the multiple journeys in which we live and come to know.Emerging Indigenous research methodological approaches are centring Indigenous wa
Contribution of Tregs to the promotion of constructive remodeling after decellularized extracellular matrix material implantation
Host remodeling of decellularized extracellular matrix (dECM) material through the appropriate involvement of immune cells is essential for achieving functional organ/tissue regeneration.As many studies have focused on the role of macrophages, only few have evaluated the role of regulatory T cells (Tregs) in dECM remodeling.In this study, we used a
Anti-CTLA-4 and anti-PD-1 immunotherapies repress tumor progression in preclinical breast and colon model with independent regulatory T cells response
The recent development of immunotherapy represents a significant breakthrough in cancer therapy.Several immunotherapies provide robust efficacy gains in a wide variety of cancers.However, in some patients the immune checkpoint blockade remains ineffective due to poor therapeutic response and tumor relapse.An improved understanding of the mechanisms
(E)-1-(Pyridin-2-yl)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one
In the title heteroaryl chalcone derivative, C17H17NO4, the dihedral angle between the pyridine and benzene rings is 10.82 (5)°.The two Bud Vase methoxy groups at the meta positions are essentially coplanar with the attached benzene rings [C—O—C—C torsion angles = −0.97 (14) and 1